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Agent Skill

Rfdiffusion Nim skill

rfdiffusion-nimNVIDIA/skillsskills/bionemo-rfdiffusion-nim/SKILL.md

Run RFDiffusion protein backbone design via NVIDIA NIM. Use for de novo protein backbones, motif scaffolding, binder design, hotspot residues, contigs syntax, diffusion steps, hosted NVIDIA API calls, local Docker deployment, and PDB backbone outputs for ProteinMPNN sequence design.

3.7kApache-2.0

always on

66 tokname + description

once used

1,439 tokSKILL.md body

bundled files

1234 KB

repo stars

3.7kGitHub

Install the Rfdiffusion Nim skill

Skills CLI (Claude Code, Codex, Cursor and others)

npx skills add https://github.com/NVIDIA/skills --skill rfdiffusion-nim

Claude Code, by hand (all projects)

git clone --depth 1 https://github.com/NVIDIA/skills.git /tmp/skills
mkdir -p ~/.claude/skills
cp -R /tmp/skills/skills/bionemo-rfdiffusion-nim ~/.claude/skills/rfdiffusion-nim

For one project only, copy the folder into .claude/skills/ in that project instead. The agent picks it up when a task matches its description.

What it costs your context

Agent Skills load in three steps. Tokens counted with the o200k tokenizer; your model's count will differ a little.

WhenWhat loadsCost
Every sessionName and description66 tok
When the agent uses itThe SKILL.md instructions1,439 tok
Only if opened12 bundled files (34 KB)varies

Until it is used, rfdiffusion-nim costs about 21× less than the median MCP server we measured (1,363 tokens on every turn). Installing all 150 skills from NVIDIA/skills would load 20,796 tokens of descriptions. Skills vs MCP study

Checks

  • The name doesn't match its folder name, as the specification requires.

Pre-approved tools (allowed-tools): Bash, Read, Write, AskUserQuestion. The agent can use these without asking while the skill is active.

Checked 2026-10-22 · method

What's inside

The headings of its SKILL.md. Read the full file on GitHub.

  • RFDiffusion NIM
  • Choose Mode
  • Local Docker
  • Contigs DSL
  • Request Pattern
  • Save And Interpret Output
  • Limits And Troubleshooting

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