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Agent Skill

Proteinmpnn Nim skill

proteinmpnn-nimNVIDIA/skillsskills/bionemo-proteinmpnn-nim/SKILL.md

Run ProteinMPNN inverse folding via NVIDIA NIM to design protein sequences for a target backbone. Sends user-provided PDB files and design parameters to NVIDIA's hosted API, authenticated with an environment API key, or to a user-selected local NIM. Use for sequence design, backbone redesign, fixed chains and residues, omit_AAs, sampling temperature, soluble model, local Docker, and multi-FASTA output.

3.7kApache-2.0

always on

90 tokname + description

once used

1,710 tokSKILL.md body

bundled files

223 scripts

repo stars

3.7kGitHub

Install the Proteinmpnn Nim skill

Skills CLI (Claude Code, Codex, Cursor and others)

npx skills add https://github.com/NVIDIA/skills --skill proteinmpnn-nim

Claude Code, by hand (all projects)

git clone --depth 1 https://github.com/NVIDIA/skills.git /tmp/skills
mkdir -p ~/.claude/skills
cp -R /tmp/skills/skills/bionemo-proteinmpnn-nim ~/.claude/skills/proteinmpnn-nim

For one project only, copy the folder into .claude/skills/ in that project instead. The agent picks it up when a task matches its description.

What it costs your context

Agent Skills load in three steps. Tokens counted with the o200k tokenizer; your model's count will differ a little.

WhenWhat loadsCost
Every sessionName and description90 tok
When the agent uses itThe SKILL.md instructions1,710 tok
Only if opened22 bundled files (1.0 MB)varies

Until it is used, proteinmpnn-nim costs about 15× less than the median MCP server we measured (1,363 tokens on every turn). Installing all 150 skills from NVIDIA/skills would load 20,796 tokens of descriptions. Skills vs MCP study

Checks

  • Ships scripts the agent can run. Read them before installing.
  • The name doesn't match its folder name, as the specification requires.

Pre-approved tools (allowed-tools): Bash, Read, Write, AskUserQuestion. The agent can use these without asking while the skill is active.

Checked 2026-10-22 · method

What's inside

The headings of its SKILL.md. Read the full file on GitHub.

  • ProteinMPNN NIM
  • Choose Mode
  • Data Transfer and Authorization
  • Local Docker
  • Instructions
  • Examples
  • Save And Report Output
  • Limits And Troubleshooting

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