Biopython skill

Legacy error-resolution reference archive retained for migration. Do not route user tasks here; use systematic-debugging for active bug, stack-trace, and root-cause work.

Expert skill for G2 legend development - provides comprehensive knowledge about legend rendering implementation, component architecture, layout algorithms, and interaction handling. Use when implementing, customizing, or debugging legend functionality in G2 visualizations.

LQF Machine Learning Expert Guide - Routed skill for ML/Statistical Modeling with Critical Discussion Mode. Triggers on: machine learning, modeling, prediction, training, classification, regression, clustering, deep learning, neural network, model evaluation, feature engineering, hyperparameter tuning, overfitting, underfitting, baseline, ablation study, critique my approach, review my model, is this a good idea, should I use, what's wrong with, evaluate my solution, challenge my assumptions, discuss my approach Engages in critical discussion with minimum 3 rounds of iterative refinement. Challenges both user proposals and own suggestions with fact-based critique. Demands evidence and baselines before accepting solutions.

Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

Access real-time and historical stock market data, forex rates, cryptocurrency prices, commodities, economic indicators, and 50+ technical indicators via the Alpha Vantage API. Use when fetching stock prices (OHLCV), company fundamentals (income statement, balance sheet, cash flow), earnings, options data, market news/sentiment, insider transactions, GDP, CPI, treasury yields, gold/silver/oil prices, Bitcoin/crypto prices, forex exchange rates, or calculating technical indicators (SMA, EMA, MACD, RSI, Bollinger Bands). Requires a free API key from alphavantage.co.

Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design. Use when architecting complex backend systems or refactoring existing applications for better maintainability.

Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.